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Time-Restricted Eating and Its Metabolic Benefits.
Sneha Mishra1, Patress A Persons1, Andrea M Lorenzo1
1Division of Community Internal Medicine Mayo Clinic, Scottsdale, AZ 85259, USA.
Journal of Clinical Medicine
|November 25, 2023
Summary
Time-restricted eating (TRE) offers metabolic benefits by shifting the body
Area of Science:
- Metabolic health and obesity research.
- Cellular metabolism and autophagy.
- Nutritional interventions and disease management.
Background:
- Obesity is a growing global health concern requiring novel management strategies.
- Time-restricted eating (TRE) involves cycles of eating and fasting, influencing metabolic processes.
- Cellular responses like protein synthesis and autophagy are key to TRE's metabolic effects.
Purpose of the Study:
- To evaluate the current literature on the benefits of time-restricted eating (TRE) regimens.
- To clarify the role of TRE in weight management and metabolic disease treatment.
- To address controversies surrounding the efficacy of TRE.
Main Methods:
- Systematic review of existing scientific literature on time-restricted eating.
- Analysis of studies comparing TRE with calorie restriction for weight loss.
- Examination of TRE's impact on metabolic diseases like NAFLD, cancer, and cardiovascular disease.
Main Results:
- Time-restricted eating (TRE) demonstrates equivalence to calorie restriction for achieving weight loss.
- TRE positively impacts patients with nonalcoholic fatty liver disease (NAFLD).
- TRE shows beneficial effects for individuals with cancer and cardiovascular disease.
Conclusions:
- Time-restricted eating (TRE) is a viable strategy for weight management, comparable to calorie restriction.
- TRE offers significant therapeutic potential for managing metabolic and chronic diseases.
- Further research into TRE regimens is warranted to optimize clinical application.
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