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Updated: Jul 10, 2025

Microbiota of Attine Ants' Gardens: Visualizing a Microbial Landscape by Scanning Electron Microscopy
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Microbiota of Attine Ants' Gardens: Visualizing a Microbial Landscape by Scanning Electron Microscopy

Published on: October 4, 2024

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Evolution of a Pathogenic Microbiome

Pui Yin Wong1, Carmen Yip1, Daniel A Lemberg2

  • 1Discipline of Paediatrics, School of Clinical Medicine, University of NSW, Sydney 2052, Australia.

Journal of Clinical Medicine
|November 25, 2023
PubMed

Insights

Infant gut microbiome development begins before birth. This review explores factors influencing the infant microbiome, distinguishing between symbiotic and disease-associated (dysbiotic) states.

Area of Science:

  • Microbiology
  • Developmental Biology
  • Immunology

Background:

  • Microbiome development initiates prenatally via vertical transmission.
  • The infant microbiome is dynamic and influenced by numerous postnatal factors.
  • Host-microbiome interactions can be symbiotic or dysbiotic, impacting infant health.

Purpose of the Study:

  • To investigate factors contributing to a dysbiotic infant microbiome.
  • To review infant gastrointestinal microbiome development and host interactions.
  • To explore the microbiome's role in host immunity and disease association.

Main Methods:

  • Literature review of infant microbiome development.
  • Analysis of host-microbiome interactions.
  • Examination of factors leading to dysbiosis.

Main Results:

  • Early life microbial colonization is crucial for infant health.
  • Dysbiosis is linked to disease states in infants.
  • Multiple factors influence the transition from symbiosis to dysbiosis.

Conclusions:

  • Understanding infant microbiome development is key to preventing disease.
  • Factors influencing dysbiosis require further investigation.
  • Targeting the infant microbiome may offer therapeutic potential.

Keywords:
childhooddysbiosisinfantinflammatory diseasemicrobiome

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