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Psychometric Performance of Generic Childhood Multi-Attribute Utility Instruments in Preterm and Low Birthweight
Joseph Kwon1, Corneliu Bolbocean1, Olu Onyimadu1
1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.
Insights
This review evaluated health measurement tools for individuals born preterm and/or low birthweight (PLB). Evidence for psychometric performance of multi-attribute utility instruments (MAUIs) in PLB populations is limited, requiring further research.
Area of Science:
- Pediatrics
- Health Economics
- Psychometrics
Background:
- Individuals born preterm and/or low birthweight (PLB) face elevated health risks throughout life.
- Evaluating psychometric performance of generic multi-attribute utility instruments (MAUIs) is crucial for this population.
Purpose of the Study:
- To systematically review and evaluate the psychometric performance of childhood-specific or compatible MAUIs in PLB populations.
- To identify evidence gaps in the psychometric properties of these instruments.
Main Methods:
- Conducted comprehensive searches across seven databases for studies on PLB populations (pediatric and adult).
- Evaluated 18 psychometric properties using a four-part criteria rating system for generic childhood-specific or compatible MAUIs.
- Synthesized data to identify evidence gaps and summarize assessment methods and results.
Main Results:
- Analyzed 42 studies, generating 178 rating outputs for four MAUIs (17D, CHSCS-PS, HUI2, HUI3).
- HUI3 accounted for 64.0% of outputs, with 38.2% related to known-group validity.
- Significant evidence gaps were found for five psychometric properties, and reliability/proxy-child agreement were poorly represented (6.7%).
- No single MAUI demonstrated superior performance across all properties; HUI2 and HUI3 lacked content validity evidence.
Conclusions:
- The generated psychometric evidence catalogue aids in selecting appropriate MAUIs for PLB populations.
- Further psychometric research is essential to address identified evidence gaps and improve instrument selection.
Background:
Individuals born preterm (gestational age < 37 weeks) and/or at low birthweight (<2500 g) are at increased risk of health impairments from birth to adulthood. This review aimed to evaluate the psychometric performance of generic childhood-specific or childhood-compatible multi-attribute utility instruments (MAUIs) in preterm and/or low birthweight (PLB) populations.
Methods:
Searches covered seven databases, including studies that targeted childhood (aged < 18 years) and/or adult (≥18 years) PLB populations; provided psychometric evidence for generic childhood-specific or compatible MAUI(s) (any language version); and published in English. Eighteen psychometric properties were evaluated using a four-part criteria rating system. Data syntheses identified psychometric evidence gaps and summarised the psychometric assessment methods/results.
Results:
A total of 42 studies were included, generating 178 criteria rating outputs across four MAUIs: 17D, CHSCS-PS, HUI2, and HUI3. Moreover, 64.0% of outputs concerned the HUI3 MAUI, and 38.2% related to known-group validity. There was no evidence for five psychometric properties. Only 6.7% of outputs concerned reliability and proxy-child agreement. No MAUI outperformed others across all properties. The frequently applied HUI2 and HUI3 lacked content validity evidence.
Conclusions:
This psychometric evidence catalogue should inform the selection of MAUI(s) suited to the specific aims of applications targeting PLB populations. Further psychometric research is warranted to address the gaps in psychometric evidence.
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