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Updated: Jul 10, 2025

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Preimplantation Genetic Testing for Genetic Diseases: Limits and Review of Current Literature
Roberta Giuliano1, Anna Maione2, Angela Vallefuoco3
1Preimplantation Genetic Diagnosis, Department of Women's and Children's Health, University of Padova, 35128 Padova, Italy.
Abstract:
Preimplantation genetic testing (PGT) has emerged as a revolutionary technique in the field of reproductive medicine, allowing for the selection and transfer of healthy embryos, thus reducing the risk of transmitting genetic diseases. However, despite remarkable advancements, the implementation of PGT faces a series of limitations and challenges that require careful consideration. This review aims to foster a comprehensive reflection on the constraints of preimplantation genetic diagnosis, encouraging a broader discussion about its utility and implications. The objective is to inform and guide medical professionals, patients, and society overall in the conscious and responsible adoption of this innovative technology, taking into account its potential benefits and the ethical and practical challenges that it presents.
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