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Updated: Jul 10, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

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The volume regulated anion channel VRAC regulates NLRP3 inflammasome by modulating itaconate efflux and mitochondria

Xiaoyan Wu1, Xin Yi1, Boxin Zhao2

  • 1Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.

Pharmacological Research
|November 25, 2023
PubMed

Keywords:
Cell volume regulationImmunometabolismInnate immunityLRRC8Macrophage activationSepsis

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