Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leuko-araiosis.

V C Hachinski, P Potter, H Merskey

    Archives of Neurology
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Deep white-matter changes are linked to cognitive impairment and vascular disease, not just Binswanger's disease. A new term, "leuko-araiosis," is proposed for precise clinical and imaging descriptions of these brain alterations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Arerugi = [Allergy]·2023
    Same author

    Geroprotectors: A role in the treatment of frailty.

    Mechanisms of ageing and development·2019
    Same author

    Life-threatening hereditary angio-oedema: Challenges of care in South Africa.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2018
    Same author

    The international WAO/EAACI guideline for the management of hereditary angioedema-The 2017 revision and update.

    Allergy·2018
    Same author

    Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    Clinical and translational allergy·2017
    Same author

    ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.

    Clinical and translational allergy·2017
    Same journal

    Incorrect Table Entries and Word.

    Archives of neurology·2016
    Same journal

    IDEAL for CCSVI Research-Reply.

    Archives of neurology·2013
    Same journal

    Atlas of Inherited Metabolic Diseases, 3rd ed.

    Archives of neurology·2013
    Same journal

    Error in byline: in heterogeneity of coenzyme q10 deficiency: patient study and literature review.

    Archives of neurology·2013
    Same journal

    This month in archives of neurology.

    Archives of neurology·2013
    Same journal

    About this journal.

    Archives of neurology·2013
    See all related articles

    Area of Science:

    • Neurology
    • Neuroimaging
    • Gerontology

    Background:

    • Deep white-matter changes are frequently observed in neuroimaging studies.
    • Their precise definition and etiological association in the literature remain ambiguous.
    • Current terminology may lead to oversimplification, such as sole identification with Binswanger's disease.

    Purpose of the Study:

    • To critically appraise the literature regarding deep white-matter changes.
    • To explore the association of these changes with cognitive impairment and vascular disease.
    • To propose a new, precise term for describing white-matter changes.

    Main Methods:

    • Literature review and critical analysis of existing studies on white-matter changes.
    • Examination of etiological factors and relationships with neurodegenerative diseases like Alzheimer's disease.

    Related Experiment Videos

  • Linguistic and historical analysis for term derivation.

    • Main Results:

    • Evidence suggests deep white-matter changes are associated with cognitive impairment and vascular disease.
    • The exclusive link to Binswanger's disease is deemed insufficient and inaccurate.
    • A need for a neutral, descriptive, and clinically demanding term is identified.

    Conclusions:

    • Deep white-matter changes represent a significant finding beyond Binswanger's disease, correlating with cognitive and vascular health.
    • The proposed term "leuko-araiosis" offers a more accurate and descriptive label for these findings.
    • Adoption of "leuko-araiosis" will enhance precision in clinical diagnosis and neuroimaging research.