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Published on: May 10, 2020
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Planet of the apex
Francesco Pellegrini1, Maria Basciu2, Rod Foroozan3
1Department of Ophthalmology, ASFO, Pordenone, PN, Italy.
Survey of Ophthalmology
|November 25, 2023
Summary
A patient with diabetes developed cranial nerve palsies, initially diagnosed as diabetic III nerve palsy. Further evaluation revealed orbital apex syndrome due to recurrent nasopharyngeal carcinoma, emphasizing accurate diagnosis.
Area of Science:
- Neuro-ophthalmology
- Oncology
- Neurology
Background:
- Diabetic III nerve palsy typically presents with isolated ptosis and exotropia.
- Orbital apex syndrome involves multiple cranial nerves and can mimic other conditions.
Observation:
- A 63-year-old male with diabetes presented with unilateral ptosis and exotropia.
- Initial diagnosis was isolated diabetic III nerve palsy.
- Subsequent evaluation revealed multiple cranial nerve involvement, indicative of orbital apex syndrome.
Findings:
- The patient had a history of nasopharyngeal carcinoma.
- Biopsy confirmed tumor recurrence as the cause of orbital apex syndrome.
- This case underscores the importance of a thorough medical history.
Implications:
- Accurate diagnosis in neuro-ophthalmology relies on detailed patient history and correlating clinical signs with anatomical structures.
- Recurrent nasopharyngeal carcinoma can manifest with complex neuro-ophthalmic symptoms.
- Prompt identification and management of tumor recurrence are crucial for patient outcomes.
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