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[Management of Cast Nephropathy]

Emanuele De Simone1, Roberta Fenoglio1, Simone Cortazzi1

  • 1University Center of Excellence on Nephrological, Rheumatological and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) including Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley (North-West Italy), San Giovanni Bosco Hub Hospital, ASL Città di Torino and Department of Clinical and Biological Sciences of the University of Turin, Turin, Italy.

Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
|November 26, 2023
PubMed
Summary

Myeloma cast nephropathy, a common cause of kidney injury in multiple myeloma patients, is primarily managed with clone-based therapy to reduce light chain production. Adjuvant strategies include increasing urine flow and alkalinization, while extracorporeal light chain removal remains under investigation.

Keywords:
cast nephropathydialysismultiple myeloma

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