Related Experiment Video

Updated: Jul 10, 2025

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.2K

Routine childhood immunization in Sub-Saharan Africa: addressing parental vaccine hesitancy

N Fadl1, S A Abdelmoneim2, A Gebreal3

  • 1Family Health Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt.

Public Health
|November 26, 2023
PubMed

Insights

Parental vaccine hesitancy (VH) affects 21.2% of parents in Sub-Saharan Africa. Interventions targeting urban residency, child health, and maternal factors like antenatal care are crucial for improving childhood immunization coverage.

Area of Science:

  • Global Health
  • Pediatrics
  • Public Health Policy

Background:

  • Parental vaccine hesitancy (VH) poses a significant challenge to achieving high childhood immunization rates globally.
  • Understanding the specific determinants of VH in diverse populations is essential for developing effective public health strategies.

Purpose of the Study:

  • To identify the key factors contributing to parental VH towards routine childhood immunizations.
  • To analyze the mediating role of VH in the relationship between maternal characteristics and vaccination uptake in Sub-Saharan Africa.

Main Methods:

  • A cross-sectional study involving 5032 parents of children aged 19 months to 6 years in 12 Sub-Saharan African countries.
  • Data collected via anonymous online surveys and face-to-face interviews using the Parent Attitude about Childhood Vaccine Scale.
  • Multivariate regression and mediating analyses were employed to identify determinants and mediation effects.

Main Results:

  • 21.2% of parents exhibited hesitancy towards routine childhood immunizations.
  • Factors increasing VH included urban residency, non-first-born children, and chronically ill children.
  • Higher maternal education, antenatal care (ANC) visits, and facility-based delivery were associated with decreased VH.
  • VH mediated the effects of ANC and maternal age on vaccination uptake, reducing uptake likelihood.

Conclusions:

  • Targeted, context-specific interventions are necessary to address parental VH.
  • Improving access to ANC and facility-based delivery may help reduce VH and increase vaccine acceptance.
  • Strategies should consider socio-demographic and child-specific factors influencing parental decisions on vaccination.
Abstract

Keywords:
Basic vaccinesCompulsory vaccinesParental attitudeRoutine immunizationSub-Saharan AfricaVaccine hesitancy

More Related Videos

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

16.8K
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.6K

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
44.6K
Cross-reactivity00:42

Cross-reactivity

Overview
31.1K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
947
Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
924
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
103