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Correlation between Demodex species in primary and recurrent chalazia
S Diener-Kudisch1, L Ramírez-Barajas1, J M Perezpeña-Diazconti2
1Departamento de Oculoplástica, Instituto de Oftalmología Fundación Conde de Valenciana, Mexico City, Mexico.
Archivos De La Sociedad Espanola De Oftalmologia
|November 26, 2023
Summary
Recurrent chalazia are strongly linked to Demodex mite infestation, particularly Demodex folliculorum. Primary chalazia showed no significant correlation with Demodex spp. infestation.
Area of Science:
- Ophthalmology
- Parasitology
- Microbiology
Background:
- Chalazia are common eyelid inflammations.
- Demodex mites are frequently found on human skin and eyelids.
Purpose of the Study:
- To investigate the association between Demodex mite infestation and the occurrence of primary and recurrent chalazia.
Main Methods:
- A prospective, observational study involving 68 adult patients with chalazia.
- Eyelash samples were analyzed for Demodex spp. presence.
- Spearman's rank correlation coefficient was used to assess the relationship.
Main Results:
- Demodex spp. were found in 63.2% of all chalazia cases.
- Recurrent chalazia showed a significant positive correlation (r=0.665, P<.05) with Demodex infestation (50% prevalence).
- Primary chalazia had a non-significant correlation with Demodex infestation (18.5% prevalence).
Conclusions:
- A significant, high correlation exists between recurrent chalazia and Demodex spp. infestation.
- No statistically significant correlation was found between primary chalazia and Demodex spp. infestation.

