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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Updated: Jul 10, 2025

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
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Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

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Advanced Triple-Negative Breast Cancer.

Grisma Patel1, Alison Prince2, Mark Harries3

  • 1Medical Oncology Specialist Registrar, Doctor - Department of Oncology, Guys Cancer Centre, Guys and St Thomas' NHS Foundation Trust, London, UK.

Seminars in Oncology Nursing
|November 26, 2023
PubMed
Summary
This summary is machine-generated.

Advances in treating advanced triple-negative breast cancer (TNBC) include new immunotherapies and targeted agents. Multidisciplinary care and nursing support are crucial for patients facing this aggressive disease.

Keywords:
Antibody–drug conjugateImmunotherapySpecialist nurseTargeted therapyTriple-negative breast cancer

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Area of Science:

  • Oncology
  • Translational Research

Background:

  • Triple-negative breast cancer (TNBC) is an aggressive subtype with a poorer prognosis.
  • Understanding TNBC heterogeneity and signaling pathways is critical for treatment development.

Approach:

  • Review of peer-reviewed literature, clinical guidelines, and trial data.
  • Focus on novel therapeutic strategies and multidisciplinary patient management.

Key Points:

  • Chemotherapy is no longer the sole treatment for TNBC.
  • Emerging therapies include immunotherapy, targeted agents, and antibody-drug conjugates.
  • Multidisciplinary care is essential for optimal patient outcomes.

Conclusions:

  • New systemic therapies are expanding treatment options for advanced TNBC.
  • Nurses play a vital role in educating patients about new treatments and managing toxicities.
  • Addressing physical and psychosocial needs through comprehensive support services is paramount.