Related Experiment Video
Updated: Jul 10, 2025
A Minimally Invasive, Accurate, and Efficient Technique for Intrathymic Injection in Mice
Published on: August 23, 2022
Observation on cadavers and through ultrasonography using a 2 mm needle length for intradermal injections
Kyu-Ho Yi1,2, Brian Lee3, Michael James Kim4
1Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, South Korea.
Background:
An intradermal injection is a medical procedure that involves administering a small amount of medication or substance into the dermal layer of the skin. This research focused on identifying the most suitable injection needle for precise intradermal administration of skin boosters.
Methods:
The study involved conducting intradermal injections on four cadavers and participants using a 2 mm length, 34-gauge needle (N-Finders, Inc., South Korea). During the cadaveric study, the polynucleotide prefilled syringe was dyed green, and an anatomist performed dissections, removing only the skin layer. Ultrasonographic observations were carried out to ensure accurate intradermal injection placement.
Results:
In all four cadavers, the facial injections at the anterior cheek region were precisely administered intradermally at a 30-degree injection angle. However, the 90-degree injection was found just below the dermal layer upon skin layer removal.
Discussion:
The findings suggest that using a 2 mm needle length allows for easy and convenient intradermal injections.
