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Global Research Trends in Limb Salvage Surgery for Osteosarcoma: Findings from a Bibliometric and Visualized Analysis
Manish Raj1, Amiy Arnav2, Arup Kumar Pal3
1Department of Orthopaedics, All India Institute of Medical Sciences, Deoghar, India.
Background:
Limb salvage surgery in osteosarcoma requires a multidisciplinary team of experts, due to which research interest has remained limited globally. This article analyzes research trends over 15 years from 2007 to 2022.
Materials And Methods:
Publications on limb salvage surgery in osteosarcoma were retrieved using the Web of Science. Bibliometric analysis of the publication metadata was done using R software. VOS viewer software was used to analyze the bibliographic coupling, co-citation, co-authorship, and co-occurrence to report the current trends in global research on limb salvage surgery in osteosarcoma.
Results:
A total of 693 articles were retrieved. On applying the inclusion and exclusion criteria, a publication metadata of 276 articles was analyzed using the methodology mentioned. Annual scientific production on the subject has shown a steady rising trend globally. China has the highest number of publications on the topic; however, the USA has the highest citations globally. The Journal "Clinical Orthopedics and Related Research" remains the pioneer in the topic with the highest number of publications and H index among all journals. Most of the research interest is generated in the developed countries of the USA, Europe, and China. Keyword analysis suggested 4 clusters of surgical reconstruction, Survival, Chemotherapy, and general management related. Newer keywords such as biological reconstructions, allograft, metastases, cell, and chemotherapy suggest future research topics in the field.
Conclusion:
Research interest in limb salvage surgery in osteosarcoma continues to grow with the introduction of concepts such as biological reconstructions and allografts. However, for more inclusive research on the topic, research interest must also be encouraged in underdeveloped and developing countries.
Insights
Research on limb salvage surgery for osteosarcoma is growing, with increasing publications from China and high citations from the USA. Future research may focus on biological reconstructions and allografts.
Area of Science:
- Orthopedics
- Oncology
- Bibliometrics
Background:
- Limb salvage surgery for osteosarcoma is complex, requiring a multidisciplinary team.
- Global research interest in this area has historically been limited.
- This study analyzes research trends from 2007 to 2022.
Purpose of the Study:
- To analyze global research trends in limb salvage surgery for osteosarcoma.
- To identify key research areas, leading countries, and influential journals.
- To highlight emerging research topics and future directions.
Main Methods:
- Bibliometric analysis of 276 articles retrieved from Web of Science.
- Utilized R software for metadata analysis.
- Employed VOS viewer for analyzing bibliographic coupling, co-citation, co-authorship, and co-occurrence.
Main Results:
- A steady global increase in scientific production on the topic.
- China leads in publications; the USA leads in citations.
- "Clinical Orthopedics and Related Research" is the leading journal.
- Research is concentrated in developed countries (USA, Europe, China).
- Keyword analysis revealed clusters in surgical reconstruction, survival, chemotherapy, and management.
- Emerging keywords include biological reconstructions, allograft, and metastases.
Conclusions:
- Research interest in limb salvage surgery for osteosarcoma is expanding, driven by innovations like biological reconstructions and allografts.
- There is a need to foster research in underdeveloped and developing countries for more inclusive global efforts.
