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Updated: Jul 10, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
Recent advances for treatment of upper gastrointestinal malignancy
Michael Sestito1, Hillary Pratt2,3, Carl Schmidt1,3
1Department of Surgery, West Virginia University, Morgantown, West Virginia, USA.
Abstract:
Recent prospective trials for esophageal cancer, gastric cancer, and gastrointestinal stromal tumor (GIST) are encouraging. This manuscript reviews selected recently published studies. Not surprisingly, immunotherapy dominates the current clinical trial landscape. However, targeted biologic therapies and standard chemotherapy remain critical to the treatment of gastric and esophageal cancer while imatinib remains the backbone for advanced or metastatic GISTs. For all three cancers, surgical resection remains important when intent of treatment is potential cure.
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