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Updated: Jul 9, 2025

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Highly malignant endometrial stromal sarcoma in a cat
Teruaki Hirota1, Kayoko Yonemaru1, Mitsunobu Hattori2
1Laboratory of Veterinary Pathology, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Journal of Comparative Pathology
|November 27, 2023
Summary
A Persian cat was diagnosed with endometrial stromal sarcoma (ESS), a rare uterine tumor. This high-grade cancer showed aggressive features, including invasion and lymphovascular spread, mirroring human ESS cases.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
- Reproductive Pathology
Background:
- Uterine tumors are uncommon in domestic animals.
- Endometrial stromal sarcoma (ESS) is a rare malignant neoplasm originating from the endometrial stroma.
- This case presents a unique instance of ESS in a feline patient.

