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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Upper Paleolithic tuberculosis: A probable case illustrated by paleoimaging methods (Azilian site of Les Iboussières,
Hélène Coqueugniot1, György Pálfi2, Bernard Gély3
1UMR 5199 PACEA, Université de Bordeaux, Allée Geoffroy Saint-Hilaire, 33615, Pessac Cedex, France; Ecole Pratique des Hautes Etudes, PSL Université Paris, 4-14 rue Ferrus, 75015, Paris, France.
Abstract:
The aim of this paper is to present the results of μCT-scan and 3D imaging analyses of two skeletal lesions observed on human remains of one of the last European hunter-gatherers from the late Paleolithic (Azilian period): a sacroiliac osteoarthritis and a femoral lesion suggestive of a soft tissue abscess imprint. These two skeletal elements (fused left sacrum and coxal bone, and right femur) displayed osteometric criteria indicating that they belonged to the same individual. These two associated lesions are consistent with a low-grade osteoarticular infection, and suggest a diagnosis of pelvic tuberculosis with a cold abscess of the thigh. If molecular confirmation is obtained, this case would be the first evidence of tuberculosis among Upper Palaeolithic populations.
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