A bibliometric analysis of cardiomyocyte apoptosis from 2014 to 2023: A review

Rui Wang1, Xu Luo1, Songyun Li1

  • 1Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Medicine
|November 28, 2023
PubMed

Insights

This bibliometric study analyzes cardiomyocyte apoptosis research, revealing key areas like molecular mechanisms and cardiac regeneration. Emerging frontiers include the NOD-like receptor protein 3 inflammasome, circular RNA, and sepsis, guiding future cardiovascular disease research.

Area of Science:

  • Cardiovascular Biology and Disease Research

Background:

  • Cardiomyocyte apoptosis significantly contributes to cardiac dysfunction in cardiovascular diseases.
  • Understanding research progress in cardiomyocyte apoptosis is crucial for advancing cardiovascular medicine.

Approach:

  • A bibliometric analysis of 5939 articles from the Web of Science database was performed.
  • VOSviewer and Citespace software were utilized for scientometric analysis of publications.
  • The study mapped author, country, institutional, and keyword networks to identify research collaborations.

Key Points:

  • Current research hotspots include experimental studies, molecular mechanisms, pathophysiology, and cardiac regeneration related to cardiomyocyte apoptosis.
  • Emerging research frontiers focus on NOD-like receptor thermal protein domain associated protein 3 inflammasome, circular RNA, and sepsis.
  • The analysis identified cooperative relationships and trends within the field.

Conclusions:

  • This bibliometric analysis provides valuable insights into the current landscape and future directions of cardiomyocyte apoptosis research.
  • The findings highlight potential areas for clinical application and further investigation in cardiovascular disease management.

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