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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
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Vasospasm in Pediatric Subarachnoid Hemorrhage
Ioannis Mavridis1, Efstratios-Stylianos Pyrgelis2, Eleni Agapiou3
1Pediatric Neurosurgery Unit, Department of Neurosurgery, School of Medicine, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis, Greece.
CNS & Neurological Disorders Drug Targets
|November 28, 2023
Summary
Cerebral vasospasm (CV) after subarachnoid hemorrhage (SAH) is less common in children but can be serious. Management includes supportive care, medications, and neurointerventions, with generally favorable outcomes.
Area of Science:
- Neurology
- Pediatric Critical Care
- Neurosurgery
Background:
- Cerebral vasospasm (CV) is a severe complication of subarachnoid hemorrhage (SAH).
- CV is less common in children than adults but can be devastating.
- Pathophysiology involves molecular and inflammatory phenomena, with protective factors like collateral circulation in children.
Purpose of the Study:
- To review current literature on cerebral vasospasm in children following subarachnoid hemorrhage.
- To outline the presentation, diagnosis, and management of pediatric CV.
Main Methods:
- Literature review of cerebral vasospasm in pediatric subarachnoid hemorrhage.
- Analysis of diagnostic imaging techniques.
- Review of current management strategies.
Main Results:
- Pediatric CV may be asymptomatic or present with altered neurologic status.
- Diagnosis confirmed by imaging showing >50% arterial caliber reduction.
- Management includes supportive care, calcium channel blockers, and neurointerventions.
Conclusions:
- Cerebral vasospasm in children post-SAH requires prompt diagnosis and management.
- While less common, pediatric CV necessitates specific consideration.
- Long-term outcomes for children experiencing CV are generally favorable.
Keywords:
Aneurysmangiographycerebral vasospasmnimodipinesubarachnoid hemorrhagetranscranial Doppler ultrasonography.
