Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pharmacovigilance

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Diabetes: Symptoms, Diagnosis, and Complications

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Psychoneuroimmunology: Diabetes and Cancer

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

Insulin: Dosing Regimen and Adverse Effects

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Primary Care Endocrinologist.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

ACEing the person-centred choice of anti-obesity therapy.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

The Flavonoids Hesperidin and Diosmin: Adjuvant Therapy for Obesity.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

Androgenemia Nervosaon.

JPMA. The Journal of the Pakistan Medical Association·2026

Same author

Onset of millennial climate variability with the intensification of Northern Hemisphere glaciation.

Science (New York, N.Y.)·2026

Same author

Glucodynia.

JPMA. The Journal of the Pakistan Medical Association·2025

Search research articles

Related Experiment Video

Updated: Jul 9, 2025

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Psychovigilance In Diabetes.

Sanjay Kalra¹, Komal Verma², Navneet Agrawal³

¹Department of Endocrinology, Bharti Hospital, Karnal, India, University Center for Research & Development, Chandigarh University, India.

JPMA. the Journal of the Pakistan Medical Association

|November 28, 2023

Summary

Diabetes patients often face mental health issues like depression, which worsen blood sugar control. Early screening, diagnosis, and management of these mental health conditions, termed psychovigilance, are crucial for better diabetes care.

Keywords:

Anxiety, depression, diabetes distress, psychosocial aspects, type 1 diabetes, type 2 diabetes.

More Related Videos

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Related Experiment Videos

Last Updated: Jul 9, 2025

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Area of Science:

Endocrinology
Psychiatry
Public Health

Background:

Diabetes mellitus is frequently comorbid with various mental health disorders, including depression, anxiety, and substance abuse.
These mental health conditions can negatively impact glycemic control and overall diabetes management.
The bidirectional relationship between diabetes and mental health necessitates integrated care strategies.

Purpose of the Study:

To introduce and define the concept of psychovigilance.
To emphasize the importance of screening, early diagnosis, and timely management of mental health dysfunction in diabetic patients.
To advocate for a proactive approach to address the mental health burden in diabetes care.

Main Methods:

Literature review on the intersection of diabetes and mental health.
Conceptualization of psychovigilance as a clinical strategy.
Discussion of the implications for patient care and outcomes.

Main Results:

Mental health challenges are prevalent in diabetes populations.
Poor mental health exacerbates hyperglycemia and complicates diabetes management.
Psychovigilance offers a framework for integrated care.

Conclusions:

Integrating mental health screening and management into routine diabetes care is essential.
Psychovigilance can improve patient outcomes by addressing the mental health comorbidities of diabetes.
Early intervention in mental health dysfunction is key to optimizing diabetes control.