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Updated: Jul 9, 2025

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
Development and Analysis of Multiscale Models for Tuberculosis: From Molecules to Populations
Multiscale modeling, integrating within-host dynamics, is crucial for combating drug-resistant infections and responding to epidemics. This approach enhances understanding and intervention strategies for complex diseases like tuberculosis.
Area of Science:
- Computational Biology
- Epidemiology
- Mathematical Modeling
Background:
- Traditional macro-scale analysis of infectious diseases is insufficient against rising drug-resistant infections.
- Within-host modeling is essential for a comprehensive understanding of epidemic dynamics.
- Multiscale modeling (MSM) offers a framework to bridge different biological scales.
Conclusions:
- Multiscale modeling is vital for understanding and responding to infectious diseases, especially drug-resistant ones.
- The presented tools (CaliPro, tunable resolution) aid in the development and application of MSMs.
- Future research directions include integrating within-host dynamics for improved treatment and epidemic response.
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10:43Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Published on: September 18, 2020
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
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