Structural and functional basis of VLDLR receptor usage by Eastern equine encephalitis virus

Lucas J Adams1, Saravanan Raju1, Hongming Ma1,2

  • 1Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Summary

Eastern equine encephalitis virus (EEEV) uses multiple sites on the very low-density lipoprotein receptor (VLDLR) for entry. A designed VLDLR decoy neutralizes EEEV infection and protects mice.