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Updated: Jul 9, 2025

Behavioral and Locomotor Measurements Using an Open Field Activity Monitoring System for Skeletal Muscle Diseases
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Case 319: Multisystemic Smooth Muscle Dysfunction Syndrome.

Catherine Wing Yan Tam1, King Kenneth Cheung1

  • 1From the Department of Radiology, North District Hospital, 9 Po Kin Road, Sheung Shui, Hong Kong (C.W.Y.T.); and Centre for Medical Imaging, University College London, London, UK (K.K.C.).

Radiology
|November 28, 2023
PubMed
Summary
This summary is machine-generated.

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A pediatric stroke case highlights recurrent neurological deficits in a young girl. This study details her complex medical history and diagnostic imaging findings.

Area of Science:

  • Neurology
  • Pediatrics
  • Medical Imaging

Background:

  • A 7-year-old girl presented with acute neurological deficits including hemiplegia and aphasia.
  • She had a history of two prior strokelike episodes and significant congenital medical conditions.
  • Her medical history included congenital mydriasis, patent ductus arteriosus, dysautonomia, and bladder dysfunction.

Purpose of the Study:

  • To report a complex pediatric stroke case with recurrent episodes.
  • To investigate the underlying causes of neurological deficits in a child with a significant medical history.

Main Methods:

  • Clinical presentation and history review.
  • Neurological examination and Glasgow Coma Scale assessment.
  • Laboratory investigations including lactate levels and coagulopathy work-up.

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  • Brain Magnetic Resonance Imaging (MRI) and MR angiography.

    • Main Results:

    • The patient exhibited right-sided hemiplegia, expressive aphasia, and reduced responsiveness.
    • Previous strokelike episodes occurred with headache, reduced movement, and numbness.
    • Initial blood tests showed mildly elevated venous lactate; coagulopathy work-up was normal.
    • Brain MRI and MR angiography were performed for diagnosis.

    Conclusions:

    • Recurrent neurological events in children warrant thorough investigation.
    • A comprehensive approach is necessary to diagnose stroke in pediatric patients with complex medical histories.
    • Advanced neuroimaging is crucial for evaluating acute neurological deficits.