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Poststroke Mania During the COVID-19 Pandemic

Takahiko Nagamine

    The Journal of Nervous and Mental Disease
    |November 28, 2023
    PubMed

    Insights

    The COVID-19 pandemic increases stress, leading to mental health issues like depression and mania. Post-stroke mania, a complication of COVID-19 infection, is also rising and requires medical consideration.

    Area of Science:

    • Neurology
    • Psychiatry
    • Infectious Diseases

    Background:

    • The COVID-19 pandemic has significantly impacted global mental health.
    • Increased susceptibility to various mental illnesses, including depression, suicide attempts, and mania, has been observed.

    Purpose of the Study:

    • To investigate the link between COVID-19 infection and the rise in manic episodes.
    • To explore potential neurological mechanisms, specifically ischemic stroke, contributing to mania.

    Main Methods:

    • Review of clinical observations and existing literature on COVID-19 complications.
    • Analysis of the relationship between ischemic stroke, cerebral blood flow, and manic symptoms.

    Main Results:

    • COVID-19 infection is associated with an increased risk of ischemic stroke.
    • Cerebral blood flow imbalances, resulting from lacunar infarcts, may trigger manic episodes.
    • The rise in mania during the pandemic may be attributed to both direct stress effects and secondary post-stroke complications.

    Conclusions:

    • COVID-19 infection presents a dual risk for mania: primary due to psychological stress and secondary to ischemic stroke.
    • Understanding the neurological sequelae of COVID-19 is crucial for managing mental health during the pandemic.

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