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Updated: Jul 9, 2025
An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
[Medical rehabilitation of children with obstructive uropathy]
E V Novikova1,2,3, M A Khan1,2, E A Turova1,3
1Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine, Moscow, Russia.
Insights
Physiotherapy using sound stimulation and selective chromotherapy can improve outcomes for children with megaloureter. These novel rehabilitation technologies show high efficacy in restoring urinary tract function and renal blood flow.
Area of Science:
- Pediatric Urology
- Rehabilitation Medicine
- Medical Technology
Abstract:
Obstructive uropathy in children is predominantly urinary system malformation and one of the leading causes of chronic renal failure. Antenatal ultrasound can detect obstructive uropathy in infants. It is important to conduct diagnostics not only to identify the obstruction level in urinary system, but to assess renal function, renal blood flow and urination. Children are given conservative and surgical treatment methods to restore urodynamics, prevent infectious complications, improve renal blood flow. Currently, there are no principles, approaches and technologies for medical rehabilitation of patients with obstructive uropathy, therefore, the use of selective chromotherapy, which has an activating effect on regional circulation, and sound stimulation improving muscles tone of pelvis and ureters, is pathogenetically reasonable and promising.
Objective:
To develop technologies of physiotherapy application (sound stimulation, selective chromotherapy) for inclusion in comprehensive medical rehabilitation of children with megaloureter.
Material And Methods:
Clinical observations and special examinations have been performed in 90 children with megaloureter aged from 1 to 10 years. The patients were divided into 2 groups: 30 children (study group) received sound stimulation combined with selective chromotherapy; 30 children (the 1st comparison group) - sound stimulation; 30 children (the 2nd comparison group) - selective chromotherapy (blue spectrum). General clinical methods, ultrasound of kidneys and bladder with Doppler monitoring of intrarenal blood flow, functional methods of bladder examination were used.
Results:
The positive effects of separate and combined application of sound stimulation and selective chromotherapy on clinical and laboratory indicators, urodynamics of urinary tract and renal blood flow in children with megaloureter after surgery have been revealed. The efficacy of selective chromotherapy use in children with megaloureter and comorbid neurologic bladder dysfunction has been proven.
Conclusion:
Modern technologies for the application of physiotherapy, namely selective chromotherapy and sound stimulation, to include them in the comprehensive medical rehabilitation of children with megaloureter, have been developed for the first time and their high efficacy has been proven.
