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Otto Emil Nyquist1, Jakob Dalgaard2, Signe Spetalen3

  • 1Cancer and Hematology Center, Vestfold Hospital Trust, Tønsberg, Norway.

British Journal of Haematology
|November 28, 2023
PubMed
Abstract

No abstract available in PubMed .

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...

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