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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Preterm Birth and Infantile Appendicitis.

Yakun Liu1, Xiaoxiao Yu2, Guoqing Zhang3

  • 1General Surgery Department, Children's Hospital of Soochow University, Soochow, Jiangsu, China.

Pediatrics
|November 29, 2023
PubMed
Summary

Preterm infants face a higher risk of developing appendicitis in their first year. Recognizing a preterm birth history can aid in earlier diagnosis of this condition in infants.

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Area of Science:

  • Pediatric Surgery
  • Neonatology
  • Gastroenterology

Background:

  • Infantile appendicitis is a rare but serious condition requiring prompt diagnosis and surgical intervention.
  • Factors influencing the risk of appendicitis in infants are not fully understood.
  • Preterm birth is a significant developmental factor that may impact infant health outcomes.

Purpose of the Study:

  • To determine if preterm birth is associated with an increased risk of appendicitis in infants.
  • To identify other risk factors for infantile appendicitis.
  • To assess the impact of preterm birth on the severity of appendicitis, specifically perforation.

Main Methods:

  • A retrospective, multicenter, matched case-control study was conducted.
  • Included were infants under 1 year of age with confirmed appendicitis (cases) and age-matched healthy controls.
  • Infants were categorized as neonates (0-28 days) or older infants (>28 days to <1 year).

Main Results:

  • Preterm birth was significantly associated with a higher risk of appendicitis in infants (adjusted odds ratio [aOR], 3.32).
  • Male sex, formula feeding, and lower weight-for-age z-scores were also associated with increased appendicitis risk.
  • Preterm birth increased appendicitis risk in both neonates (aOR, 4.56) and older infants (aOR, 3.63) but did not significantly affect perforation rates.

Conclusions:

  • Infants born preterm have a substantially increased risk of developing appendicitis within their first year of life.
  • A history of preterm birth is a valuable clinical indicator that may facilitate earlier diagnosis of infantile appendicitis.
  • Further research could explore the specific mechanisms linking preterm birth to appendicitis.