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Can uric acid affect the immune microenvironment in bladder cancer? A single-center multi-omics study

Haotian Chen1,2, Donghui Shi3, Changfeng Guo4

  • 1Department of Urology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Molecular Carcinogenesis
|November 29, 2023
PubMed
Summary

High uric acid (UA) levels are linked to worse bladder cancer (BCa) prognosis and reduced immunotherapy effectiveness. This study identifies UA as a key factor influencing BCa progression and patient survival.

Keywords:
bladder cancerhyperuricemiaimmunotherapysingle-cell RNA sequencingtumor microenvironmenturic acid

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