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Updated: Jul 27, 2026

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells
Published on: July 22, 2013
A highly selective ratio-metric fluorescent sensor for visualizing nitroreductase in hypoxic cells
Yumei Xu1, Bing Hu1, Yanjun Cui1
1Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Agriculture University, No. 1 Yingmen village, Anning District, Lanzhou, Gansu 730070, China. xuym@gsau.edu.cn.
Abstract:
Herein, we have developed a novel single-molecular probe (NORP) for selective and accurate determination of NTR in living cells. It was discovered that up-regulation of endogenous NTR occurred in response to hypoxic stimulation, and there was a dependence between the NTR levels and the degree of hypoxia.
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