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[Historical and philosophical issues in animal experimentation].
1Institut du Cerveau (ICM), GH Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France - Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), CNRS, Université Paris 1 Panthéon-Sorbonne, 13 rue du Four, 75006 Paris, France.
Animal experimentation evolved from ancient Greece to the Renaissance, with 19th-century science revealing animal sentience. Modern ethical frameworks, like the Three Rs, now guide animal research practices.
Area of Science:
- History of Science
- Bioethics
- Animal Welfare
Context:
- Animal experimentation traces roots to ancient Greece, modern practices emerged during the Renaissance.
- 19th-century scientist Claude Bernard's work influenced the ethical debate on animal use in research.
- The concept of animal sentience and consciousness parallels human experiences, raising ethical concerns.
Purpose:
- To trace the historical development of animal experimentation.
- To analyze the ethical considerations and philosophical underpinnings of animal research.
- To outline the current regulatory landscape governing animal use in science.
Summary:
- Early animal experimentation practices evolved significantly from ancient Greece to the Renaissance.
- Claude Bernard's 19th-century research highlighted animal sentience, shifting ethical perspectives.
- Contemporary ethical guidelines, including the Three Rs and European Directive 2010/63/EU, govern animal experimentation.
Impact:
- Led to increased moral concern regarding animal experimentation.
- Established legal and ethical frameworks such as the Three Rs and EU directives.
- Promoted improvements in animal treatment and encourages development of alternative methods.
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