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Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
Published on: December 29, 2021
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Phytocannabinoids: Pharmacological effects, biomedical applications, and worldwide prospection
Ana L G de Brito Siqueira1, Pedro V V Cremasco1, Juliana O Bahú2
1Institute of Science and Technology, Federal University of Alfenas (UNIFAL), Poços de Caldas, 37715-400, Minas Gerais, Brazil.
Journal of Traditional and Complementary Medicine
|November 29, 2023
Summary
Cannabis Sativa L. extracts show potential for neurological diseases like Alzheimer's and Parkinson's. Research explores its therapeutic benefits, constituents, and global market prospects, aiding symptom management.
Area of Science:
- Neurology
- Pharmacology
- Medical Cannabis Research
Background:
- Neurological diseases (e.g., Parkinson's, Alzheimer's, ALS) are increasing globally, linked to oxidative damage.
- Cannabis Sativa L. extracts are being investigated as potential palliative treatments for neurological disorders, spasticity, pain, and nausea.
Purpose of the Study:
- To review the latest developments in Cannabis use for neurological conditions.
- To discuss Cannabis subtypes, constituents, extraction methods, and pharmacological effects.
- To analyze biomedical applications, market prospects, and scientific literature from South America and Africa.
Main Methods:
- Literature review of scientific evidence on Cannabis and neurological diseases.
- Bibliometric analysis of publications from representative countries in South America and Africa.
- Discussion of pharmacological effects and market trends.
Main Results:
- Cannabis Sativa L. extracts offer potential therapeutic benefits for neurological disorders.
- (-)-trans-delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) have demonstrated proven benefits in several studies.
- The global cannabis market is projected to grow, driven by new technologies and increasing social acceptance.
Conclusions:
- Further research is needed to address evidence gaps regarding Cannabis effectiveness and safety for neurological conditions.
- Increased social acceptance and technological advancements may drive the global use and market of Cannabis extracts.
- Cannabis Sativa L. holds promise for improving quality of life in patients with neurological diseases, particularly in developing regions.
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