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A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage
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Parainfectious cerebral vasculopathy complicating bacterial meningitis: Acute-short lived vasospasm followed by

Vivig Shantha Kumar1

  • 1Department of Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Brain Circulation
|November 29, 2023
PubMed

Insights

Bacterial meningitis causes serious changes in brain arteries, leading to dangerous cerebrovascular issues. This review details the structural artery damage and its impact on blood flow during this infection.

Area of Science:

  • Neurology
  • Pathology
  • Radiology

Background:

  • Bacterial meningitis is a severe infection affecting the meninges.
  • Cerebrovascular complications are common in bacterial meningitis.

Purpose of the Study:

  • To review structural changes in cerebral arteries during bacterial meningitis.
  • To correlate these arterial changes with cerebrovascular consequences.

Main Methods:

  • Review of radiological studies on bacterial meningitis.
  • Analysis of structural alterations in cerebral vasculature.

Main Results:

  • Bacterial meningitis induces arterial vasospasm.
  • Progressive vasculitis, smooth muscle changes, necrosis, fibrosis, and stenosis occur in cerebral arteries.
  • These changes disrupt cerebral hemodynamics.

Conclusions:

  • Structural modifications of cerebral arteries are a key feature of bacterial meningitis.
  • Understanding these changes is crucial for managing cerebrovascular complications.
Keywords:
Bacterial meningitiscerebral infarctioncerebral ischemiacerebrovascular diseasevasculitisvasospasm

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