Cyclonite-Induced Seizures After Voluntary C-4 Ingestion

Area of Science:

• Toxicology
• Emergency Medicine
• Pharmacology

Background:

• Cyclonite, also known as RDX or hexogen, is the primary component in Composition 4 (C-4) plastic explosives.
• RDX has been widely utilized in military and civilian contexts since the Vietnam War due to its inherent instability.
• Its toxicological profile includes potential for euphoric effects, seizures, and severe liver and kidney damage upon ingestion or inhalation.

Observation:

• A patient presented with a generalized tonic-clonic seizure four hours post-ingestion of 75 grams of C-4.
• The patient's clinical presentation mimicked severe toxicological effects, necessitating intensive care unit admission.

Findings:

• Prompt administration of anticonvulsant medications was crucial in managing the patient's seizure activity.
• The patient demonstrated a complete recovery without long-term sequelae following stabilization.

Implications:

• This case highlights the severe neurotoxic potential of Cyclonite (RDX) exposure.
• Effective management with anticonvulsants can lead to favorable outcomes in cases of significant C-4 ingestion.
• Understanding RDX toxicity is critical for emergency medical personnel managing potential exposure incidents.