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A Case of Longitudinally Extensive Transverse Myelitis Following COVID-19 Infection
Jyotsna Gummadi1, Meika Bhattachan1, Athmananda Nanjundappa1
1Department of Medicine, MedStar Franklin Square Medical Center, Baltimore, USA.
Abstract:
One of the rare complications following acute COVID-19 infection is acute transverse myelitis (ATM). With only a few cases of ATM reported in the literature, an addition of longitudinally extensive transverse myelitis (LETM) diagnosed in our patient would underscore the complexity and diversity of neurological manifestations associated with this viral illness. A 54-year-old patient presented to the emergency department with fever, shortness of breath, nausea and vomiting. The patient's nasopharyngeal swab for COVID-19 polymerase chain reaction (PCR) resulted positive. Few days later, the patient developed bilateral upper, lower extremities weakness, back pain, urinary retention and dysphagia. Subsequently, the clinical presentation, MRI, cerebrospinal fluid (CSF) and laboratory findings pointed toward LETM as a complication of COVID-19 infection over other differentials. The aggressiveness of this disease necessitated high-dose steroids and plasmapheresis, pain control medication and rehabilitation which led to a slight improvement in the neurological symptoms at the time of discharge to the rehabilitation facility.
Insights
A rare complication of COVID-19 is acute transverse myelitis (ATM). This case highlights longitudinally extensive transverse myelitis (LETM) as a complex neurological manifestation of the viral illness.
Area of Science:
- Neurology
- Infectious Diseases
- Immunology
Background:
- COVID-19 is a viral illness with diverse neurological complications.
- Acute transverse myelitis (ATM) is a rare neurological complication of COVID-19.
Observation:
- A 54-year-old patient with COVID-19 developed severe neurological symptoms including bilateral weakness, back pain, and urinary retention.
- Clinical presentation, MRI, CSF, and laboratory findings confirmed longitudinally extensive transverse myelitis (LETM).
Findings:
- LETM was diagnosed as a complication of COVID-19 infection in this patient.
- The patient required aggressive treatment including high-dose steroids and plasmapheresis.
Implications:
- This case underscores the complexity and diversity of neurological manifestations of COVID-19.
- LETM represents a significant neurological challenge following acute COVID-19 infection.
- Early diagnosis and aggressive management are crucial for improving outcomes in COVID-19-associated LETM.
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