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Updated: Jul 31, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Unusual sites of hepatocellular carcinoma metastasis: Case report
Hunza Chaudhry1, Aalam Sohal2, Humzah Iqbal1
1Department of Internal Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Abstract:
Hepatocellular carcinoma is an increasingly frequent cause of cancer-related death. The majority of patients with hepatocellular carcinoma are asymptomatic. In rare cases, patients may present with symptoms of extrahepatic metastases. Early identification can lead to timely treatment and prevent poor outcomes. We report three cases of patients with hepatocellular carcinoma with unusual sites of metastasis, including clival, mandible, and cardiac involvement.

