Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

2.9K
The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
2.9K
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

208
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
208
Factors Affecting Solubility04:01

Factors Affecting Solubility

33.5K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
33.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Like night and day: a review of nocturnal predator communities and predation in annual row crop agroecosystems.

Annals of the Entomological Society of America·2026
Same author

Light-Programmable Morphology in Photothermal Polyurethanes Based on Stenhouse Salt as Photothermal Agent.

Journal of the American Chemical Society·2026
Same author

Effect of Financial Education and Coaching on Economic Stability in Low Income, Single Mother Families.

Journal of prevention (2022)·2026
Same author

Synergizing Chemical and AI Communities for Advancing Laboratories of the Future.

ACS central science·2026
Same author

From Lipoic Acid to 1,2-Dithianes: Expanding Radical Ring-Opening to Less-Activated Monomers Such as Vinyl Acetate.

Journal of the American Chemical Society·2026
Same author

Surface Chemistry and Particle Morphology Govern the Multiscale Interactions and Properties of Silica-Polyelectrolyte-Stabilized Microcapsules.

Langmuir : the ACS journal of surfaces and colloids·2026

Related Experiment Video

Updated: Jul 9, 2025

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

9.4K

Tethered together: DASA design towards aqueous compatibility.

Julie A Peterson1, Natalia M Neris1, Javier Read de Alaniz1

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara Santa Barbara 93106 CA USA javier@chem.ucsb.edu.

Chemical Science
|November 29, 2023
PubMed
Summary

New donor-acceptor Stenhouse adducts (DASAs) exhibit stable, reversible photoswitching in polar protic solvents, overcoming a key limitation for biological applications. This breakthrough enables their use in aqueous environments.

More Related Videos

Removal of Arsenic Using a Cationic Polymer Gel Impregnated with Iron Hydroxide
08:01

Removal of Arsenic Using a Cationic Polymer Gel Impregnated with Iron Hydroxide

Published on: June 28, 2019

7.5K
Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
09:35

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization

Published on: December 25, 2017

28.4K

Related Experiment Videos

Last Updated: Jul 9, 2025

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

9.4K
Removal of Arsenic Using a Cationic Polymer Gel Impregnated with Iron Hydroxide
08:01

Removal of Arsenic Using a Cationic Polymer Gel Impregnated with Iron Hydroxide

Published on: June 28, 2019

7.5K
Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
09:35

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization

Published on: December 25, 2017

28.4K

Area of Science:

  • Organic chemistry
  • Photochemistry
  • Materials science

Background:

  • Donor-acceptor Stenhouse adducts (DASAs) are known for tunable visible light absorption and negative photochromism.
  • Existing DASA derivatives exhibit poor performance in polar protic solvents, hindering biological applications.
  • Overcoming solvent limitations is crucial for expanding DASA utility.

Purpose of the Study:

  • To develop novel DASA derivatives with improved stability and photoswitching capabilities in polar protic solvents.
  • To enable the application of DASAs in biological systems and aqueous environments.
  • To investigate the relationship between molecular structure and solvent compatibility.

Main Methods:

  • Synthesized novel DASA derivatives with a specific substitution on the triene.
  • Investigated the photoswitching behavior of these derivatives in various polar protic solvents.
  • Analyzed the impact of charge separation on solvent stability and switching efficiency.

Main Results:

  • The new DASA derivatives demonstrate stability and high dark equilibrium in polar protic solvents.
  • Reduced charge separation in the modified DASAs allows for reversible switching in protic media.
  • Successful switching was observed in THF:water mixtures, indicating broad solvent compatibility.

Conclusions:

  • A novel strategy for synthesizing DASA derivatives compatible with polar protic solvents has been established.
  • These findings significantly advance the potential of DASAs for applications in biological and aqueous systems.
  • The developed DASAs offer a promising platform for light-controlled molecular devices in diverse environments.