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Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

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Published on: June 2, 2019

Diabetic muscle infarction: A case report.

C Levine Emma¹, K Brennan Sara², P Johnston Gregory³

¹Department of Surgery, Vanderbilt University, Nashville TN, USA.

Journal of Family Medicine and Primary Care

|November 29, 2023

Summary

Diabetes muscle infarction (DMI) is a rare diabetes complication often seen with kidney disease. Early diagnosis and varied treatment lead to quick recovery, but recurrence is possible.

Keywords:

Complications of Diabetes Diabetes Muscle Infarction

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Last Updated: Jul 9, 2025

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Published on: June 2, 2019

A Modified Surgical Model of Hind Limb Ischemia in ApoE-/- Mice using a Miniature Incision

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Area of Science:

Endocrinology
Nephrology
Radiology

Background:

Diabetes muscle infarction (DMI) is a rare but serious complication of diabetes mellitus.
Patients with DMI frequently exhibit co-existing kidney disease, highlighting a significant comorbidity.
Understanding DMI is crucial given the rising global prevalence of diabetes.

Observation:

This case report details a 36-year-old female presenting with right lower extremity pain.
The patient had a history of chronic kidney disease, a common comorbidity with DMI.
Clinical presentation included characteristic muscle pain and swelling.

Findings:

Diagnosis of DMI typically involves advanced imaging, with MRI using gadolinium contrast as the gold standard.
Laboratory studies can provide supportive evidence for DMI diagnosis.
The patient's presentation and diagnostic workup were consistent with DMI.

Implications:

Highlighting rare DMI cases is essential for clinical awareness and timely diagnosis.
Prompt diagnosis and appropriate management of DMI can lead to rapid patient recovery.
Increased prevalence of diabetes suggests a potential rise in DMI cases, necessitating further research and awareness.