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Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
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Precious metal clusters as fundamental agents in bioimaging usability
Xiaoxiao He1, Shaojun Liu2,3, Xi Hu2,3
1Department of Medical Engineering, Daping Hospital, Army Medical University, Chongqing, China.
Frontiers in Chemistry
|November 29, 2023
Summary
Precious metal clusters (PMCs) like gold, silver, and copper offer superior optical stability and tunable properties for advanced bioimaging. This review highlights their potential in biomedical applications, advancing fluorescent nanomaterial technology.
Area of Science:
- Nanomaterials Science
- Biomedical Engineering
- Optical Physics
Background:
- Fluorescent nanomaterials (NMs) are crucial for biomedical imaging.
- Precious metal clusters (PMCs) such as gold (Au), silver (Ag), and copper (Cu) NMs are emerging as advanced imaging agents.
- PMCs offer advantages over traditional fluorescent molecules, including high optical stability, size/shape tunability, and multifunctionality.
Purpose of the Study:
- To review recent advancements in the bioimaging applications of fluorescent nanomaterials.
- To provide a comprehensive overview of precious metal clusters (Au, Ag, Cu) and their applications in bioimaging.
- To explore novel ideas for fluorescent NMs in bioimaging, including rare earth element-doped heterogeneous structures.
Main Methods:
- Literature review of recent research on fluorescent nanomaterials in bioimaging.
- Analysis of optical properties and photoluminescent characteristics of precious metal clusters.
- Examination of specific examples of PMCs and rare earth element-doped structures in biomedical imaging.
Main Results:
- Precious metal clusters exhibit excellent photoluminescence, photostability, and sub-nanometer size.
- PMCs demonstrate significant potential as fundamental agents in bioimaging systems.
- Rare earth element-doped heterogeneous structures show promise for innovative biomedical imaging.
Conclusions:
- Fluorescent precious metal clusters are highly promising for advanced bioimaging applications.
- Further research into PMCs and novel NM structures can drive innovation in biomedical imaging.
- This review provides a generalized overview of PMC applications, offering new ideas for fluorescent NM development.

