The incidence of depression and anxiety disorders in spontaneous chronic urticaria patients
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Published on: December 20, 2024
Anushree Bangera1, Meghna Singh1, Kiran Godse1
1Department of Dermatology, Dr. D Y Patil Medical College, Navi Mumbai, India
Insights
Chronic urticaria (CU) patients frequently experience depression and anxiety more than healthy individuals. This highlights the need to consider mental health when managing CU.
Area of Science:
- Dermatology
- Psychiatry
- Clinical Research
Background:
- Chronic urticaria (CU) significantly impacts quality of life and can cause psychological distress.
- Limited research exists on the prevalence of depression and anxiety in CU patients.
- CU is characterized by wheals, angioedema, or both.
Purpose of the Study:
- To evaluate the incidence of depression and anxiety in chronic urticaria patients.
- To compare depression and anxiety levels between CU patients and a healthy control group.
- To utilize the Hamilton Rating Scale for Depression (HDRS) and Hamilton Anxiety Rating Scale (HAMA).
Main Methods:
- Thirty CU patients and thirty healthy volunteers were included.
- The HDRS and HAMA were administered to assess depression and anxiety.
- Patient data included urticaria activity, medications, age, gender, comorbidities, employment, and income.
Main Results:
- CU patients (mean age 26.9 years) showed higher rates of moderate to severe anxiety (46%) and depression (70%) compared to controls.
- In the control group, moderate to severe anxiety was observed in 23.3% and severe depression in 26.7%.
- Significant differences in depression and anxiety levels were found between CU patients and the healthy group.
Conclusions:
- Individuals with chronic urticaria exhibit higher frequencies of depression and anxiety symptoms.
- Mental health comorbidities are common in CU patients.
- Screening for and addressing psychological distress is crucial in CU management.
Abstract:
Objective: A frequent condition known as chronic urticaria (CU) is characterized by the appearance of wheals, angioedema, or both. CU lowers the quality of life and may also result in psychological discomfort. The literature survey revealed few studies dealing with depression and anxiety in these patients. Hence, Hamilton scores for depression and anxiety were used in this study to evaluate the incidence of depression and anxiety in chronic urticaria patients. Methodology: To evaluate CU patients' levels of depression and anxiety, the Hamilton Rating Scale for Depression (HDRS) and the Hamilton Anxiety Rating Scale (HAMA) were applied. Moreover, in a control group of thirty healthy volunteers, thirty CU patients were included in this study. It was essential to observe the patients' urticaria activity score, medications, age, gender, comorbidities, employment status, and income. When it came to levels of depression and anxiety, a comparison was made between the case group and the healthy group. Results: In the CU patients' group, the mean age was 26.9 years. The questionnaires showed that 14 (46%) subjects in the patient group had moderate to severe signs of anxiety, and 21 (70%) had moderate to severe symptoms of depression. Besides, in the control group,7 (23.3%) had moderate to severe signs of anxiety, and 8 (26.7%) had severe depression. Conclusion: According to the study, individuals with CU exhibit depression and anxiety symptoms more frequently than the control group. Therefore, the possibility of mental comorbidities should be considered when treating individuals with CU.
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