The incidence of depression and anxiety disorders in spontaneous chronic urticaria patients

Anushree Bangera1, Meghna Singh1, Kiran Godse1

  • 1Department of Dermatology, Dr. D Y Patil Medical College, Navi Mumbai, India

Qatar Medical Journal
|November 29, 2023
PubMed

Insights

Chronic urticaria (CU) patients frequently experience depression and anxiety more than healthy individuals. This highlights the need to consider mental health when managing CU.

Area of Science:

  • Dermatology
  • Psychiatry
  • Clinical Research

Background:

  • Chronic urticaria (CU) significantly impacts quality of life and can cause psychological distress.
  • Limited research exists on the prevalence of depression and anxiety in CU patients.
  • CU is characterized by wheals, angioedema, or both.

Purpose of the Study:

  • To evaluate the incidence of depression and anxiety in chronic urticaria patients.
  • To compare depression and anxiety levels between CU patients and a healthy control group.
  • To utilize the Hamilton Rating Scale for Depression (HDRS) and Hamilton Anxiety Rating Scale (HAMA).

Main Methods:

  • Thirty CU patients and thirty healthy volunteers were included.
  • The HDRS and HAMA were administered to assess depression and anxiety.
  • Patient data included urticaria activity, medications, age, gender, comorbidities, employment, and income.

Main Results:

  • CU patients (mean age 26.9 years) showed higher rates of moderate to severe anxiety (46%) and depression (70%) compared to controls.
  • In the control group, moderate to severe anxiety was observed in 23.3% and severe depression in 26.7%.
  • Significant differences in depression and anxiety levels were found between CU patients and the healthy group.

Conclusions:

  • Individuals with chronic urticaria exhibit higher frequencies of depression and anxiety symptoms.
  • Mental health comorbidities are common in CU patients.
  • Screening for and addressing psychological distress is crucial in CU management.

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