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Updated: Jul 9, 2025

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally
Published on: April 25, 2025
Management strategy in actinomycosis brain abscess
Mohamed Dehmani Yedeas1,2, Mohamed Amine Rachdi1,2, Souheil Zayet2
1Neurosurgery Department Military Hospital of Tunis Tunis Tunisia.
Abstract:
We reported herein a case of isolated cerebral actinomycosis in a 54-year-old immunocompetent man. Brain MRI showed a left frontal intra-axial lesion and perilesional edema. We performed an open biopsy of the left frontal enhancing lesion. Intraoperative findings showed a yellowish, malleable, and capsulated lesion that was well defined with surrounding normal tissue within pus inside and lacked any necrotic content. MR spectroscopy showed a high level of choline, lactate, and lipid peaks with a choline/N-Acetylaspartic acid ratio of 1.8. The diagnosis was confirmed histologically, and the patient was treated successfully for 3 months after surgical aspiration. Surgical management allowed to confirm the diagnosis with a shorten antibiotics, a rapid resolution of symptoms, and a complete recovery.
Insights
This case study details a rare instance of isolated cerebral actinomycosis in an immunocompetent male. Successful treatment involved surgical aspiration and antibiotics, leading to complete recovery.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Cerebral actinomycosis is a rare fungal infection of the brain.
- It often presents with non-specific symptoms, making diagnosis challenging.
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