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Updated: Jul 9, 2025

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
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A Case of Congenital Mild Hemophilia Diagnosed After Wisdom Teeth Extraction
Yu Yoshida1,2, Isamu Kodani2
1Division of Oral Surgery, National Hospital Organization Yonago Medical Center, Yonago 683-0006, Japan and.
Abstract:
Hemophilia A is a recessive congenital deficiency of factor VIII that is characterized by normal bleeding time, normal prothrombin time, and prolonged activated partial thromboplastin time. In moderate and severe cases, abnormal bleeding is observed even after minor trauma, and the diagnosis is usually made by the age of 5-6 years, whereas in mild cases, abnormal bleeding is detected after major trauma or surgery. Herein, we present a case of hemophilia A that was discovered due to difficulties with hemostasis after tooth extraction.
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