Related Experiment Video
Updated: Jul 7, 2026

12:09
Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
Published on: May 2, 2011
42.9K
Re-purposed drive-through vaccination set-up for Mpox, New York Metropolitan Area
Marina Keller1, Vishnu Chaturvedi1, Rebecca Glassman1
1Westchester Medical Center, 100 Woods Street, Valhalla, NY 10595, USA.
Infection Prevention in Practice
|November 29, 2023
Summary
A New York medical center successfully adapted its COVID-19 drive-through site for Mpox vaccinations, administering over 1,820 Jynneos vaccine doses efficiently and safely to 1,123 individuals.
Area of Science:
- Public Health
- Infectious Disease Management
- Vaccinology
Background:
- A large medical center in New York repurposed a drive-through COVID-19 vaccination structure.
- This adaptation was in response to a surge in Mpox cases in July 2022.
Purpose of the Study:
- To detail the process of re-purposing a drive-through vaccination site for Mpox.
- To evaluate the efficiency and safety of this model for delivering Mpox vaccines.
Main Methods:
- Mpox vaccination was initiated within an existing drive-through structure already conducting COVID-19 vaccination and testing.
- Jynneos (Smallpox and Monkeypox Vaccine, Live, Non-replicating) vaccine was administered via subcutaneous and intradermal routes.
- Vaccinations were delivered to individuals in their vehicles through the open window.
Main Results:
- Over 1,820 Jynneos vaccine doses were administered to 1,123 individuals.
- The vaccination process averaged 8-10 patients per hour.
- Five vaccine recipients developed Mpox rash; no healthcare providers were exposed.
Conclusions:
- The drive-through vaccination model proved efficient for handling a surge in Mpox cases.
- This model is recommended for redeployment in future unexpected vaccine initiatives.
Related Concept Videos
Vaccinations
Overview
Cancer Vaccines
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Vaccine Production
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
Vaccines
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Poliomyelitis
Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

