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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Case Report: Integrated echocardiographic assessment guided Liwen procedure for treating obstructive hypertrophic
Rui Zhang1, Fan Zhao1, Jing Wang1
1Department of Echocardiography, First Clinical Medicine School, Gansu Province Hospital, Gansu University of Chinese Medicine, Lanzhou, China.
Insights
Hypertrophic obstructive cardiomyopathy with left ventricular apical aneurysm (HOCM-LVAA) can be treated with echocardiography-guided radiofrequency ablation. This novel approach shows promise for managing this rare, severe cardiac condition.
Area of Science:
- Cardiology
- Medical Imaging
- Genetics
Background:
- Hypertrophic cardiomyopathy (HCM) is a genetic myocardial disease with significant incidence and a leading cause of sudden cardiac death (SCD) in young athletes.
- Left ventricular apical aneurysm (LVAA) is a rare HCM subtype (approx. 5% of cases) associated with increased cardiovascular adverse events.
- Hypertrophic obstructive cardiomyopathy with LVAA (HOCM-LVAA) poses therapeutic challenges, especially when medical management is insufficient.
Abstract:
Hypertrophic cardiomyopathy (HCM) is a genetic myocardial disease, with an estimated incidence of 0.2%-6%, and is the main cause of sudden cardiac death (SCD) in young athletes. Left ventricular apical aneurysm (LVAA) is a rare subtype of HCM, accounting for about 5% of HCM patients, and has a higher incidence of cardiovascular adverse events. In cases of hypertrophic obstructive cardiomyopathy with LVAA (HOCM-LVAA) that do not respond adequately to optimized medical therapy, the echocardiography-guided percutaneous intra-myocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) emerges as a promising and effective novel therapeutic approach. In this case report, we present for the first time a comprehensive application of echocardiographic techniques, including TTE, 2-D STE, and contrast enhancement, in the diagnosis, treatment, surgical guidance, and assessment of therapeutic outcomes in a case of HOCM-LVAA.
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