Outbreak of extensively drug-resistant Serratia marcescens in an intensive care unit

Tazio Vanni1,2, Letícia Olivier Sudbrack1, Tatiana Amabile de Campos3

  • 1Núcleo de Controle de Infecção Hospitalar, Hospital de Base do Distrito Federal - Brasília, Distrito Federal, Brasil.

Insights

An extensively drug-resistant Serratia marcescens outbreak infected four trauma patients in an intensive care unit (ICU). Strict containment measures successfully controlled the spread while maintaining ICU operations.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • Outbreaks of extensively drug-resistant bacteria pose significant threats in intensive care units (ICUs).
  • Serratia marcescens is an opportunistic pathogen that can cause severe infections, particularly in vulnerable patient populations.

Purpose of the Study:

  • To investigate and control an outbreak of extensively drug-resistant Serratia marcescens in a trauma intensive care unit.
  • To describe the containment strategies implemented and their effectiveness.

Main Methods:

  • Epidemiological investigation to identify the source and transmission of the outbreak.
  • Implementation of intensive containment measures, including enhanced hygiene protocols and patient isolation.
  • Microbiological surveillance to monitor the spread of the specific bacterial strain.

Main Results:

  • Four critically ill trauma patients were infected with the same extensively drug-resistant Serratia marcescens strain over a six-week period.
  • Intensive containment measures effectively limited the further spread of the outbreak within the ICU.
  • The trauma ICU maintained its operational capacity throughout the outbreak investigation and control period.

Conclusions:

  • Rapid identification and implementation of containment strategies are crucial for controlling extensively drug-resistant bacterial outbreaks in ICUs.
  • Effective outbreak management can mitigate patient harm and ensure continued critical care services.

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