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Updated: Jul 9, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
The Characteristics, Mechanisms and Therapeutics: Exploring the Role of Gut Microbiota in Obesity
Zequn Zhuang1, Peng Zhou1, Jing Wang2
1Department of General Surgery, the Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi, People's Republic of China.
Abstract:
Presently, obesity has emerged as a significant global public health concern due to its escalating prevalence and incidence rates. The gut microbiota, being a crucial environmental factor, has emerged as a key player in the etiology of obesity. Nevertheless, the intricate and specific interactions between obesity and gut microbiota, along with the underlying mechanisms, remain incompletely understood. This review comprehensively summarizes the gut microbiota characteristics in obesity, the mechanisms by which it induces obesity, and explores targeted therapies centered on gut microbiota restoration.
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