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Gliptin-induced bullous pemphigoid
International Journal of Clinical Pharmacology and Therapeutics
|November 30, 2023
Summary
Drug-induced bullous pemphigoid (DIBP) can be triggered by dipeptidyl peptidase-4 (DPP-4) inhibitors like linagliptin. Careful drug assessment and multidisciplinary care are crucial for managing DIBP in elderly patients.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Bullous pemphigoid (BP) is a rare autoimmune blistering disease predominantly affecting the elderly.
- Drug-induced bullous pemphigoid (DIBP) is a subtype that may not resolve upon drug withdrawal.
- Dipeptidyl peptidase-4 (DPP-4) inhibitors, also known as gliptins, are increasingly implicated in DIBP.

