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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
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Tracheal hamartoma masquerading as asthma
Yanika Farrugia1, Michael Pace Bardon2, Gabriel Galea3
1Mater Dei Hospital, Msida, Malta yanika.gatt@gov.mt.
BMJ Case Reports
|November 30, 2023
Summary
A rare tracheal chondrohamartoma mimicked severe asthma in an elderly non-smoker. Surgical removal resolved respiratory symptoms, highlighting the importance of considering rare airway tumors.
Area of Science:
- Respiratory Medicine
- Thoracic Surgery
- Pulmonology
Background:
- Tracheal tumors are rare, with chondrohamartomas being benign cartilaginous neoplasms.
- Misdiagnosis of airway obstruction as asthma can delay appropriate treatment.
Observation:
- An elderly female non-smoker with a history of asthma presented with intractable cough, shortness of breath, and wheezing.
- Initial management for severe asthma for two decades failed to alleviate symptoms.
Findings:
- High-resolution CT scan revealed a large intraluminal tracheal polypoid mass.
- Flexible bronchoscopy confirmed a pedunculated mass in the distal trachea.
- Surgical removal via rigid bronchoscopy, laser, electrocautery, and argon ablation was successful.
Implications:
- This case underscores the necessity of investigating persistent respiratory symptoms unresponsive to asthma treatment.
- Early diagnosis and surgical intervention for tracheal chondrohamartoma can lead to complete symptom resolution.
- Highlights the differential diagnosis for severe asthma, especially in non-smokers.
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