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Related Concept Videos

Trachea01:22

Trachea

2.1K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
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The Bronchial Tree01:23

The Bronchial Tree

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The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
411
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Related Experiment Video

Updated: Jul 9, 2025

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

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Tracheal hamartoma masquerading as asthma.

Yanika Farrugia1, Michael Pace Bardon2, Gabriel Galea3

  • 1Mater Dei Hospital, Msida, Malta yanika.gatt@gov.mt.

BMJ Case Reports
|November 30, 2023
PubMed
Summary

A rare tracheal chondrohamartoma mimicked severe asthma in an elderly non-smoker. Surgical removal resolved respiratory symptoms, highlighting the importance of considering rare airway tumors.

Keywords:
AsthmaLung function

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Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Last Updated: Jul 9, 2025

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Area of Science:

  • Respiratory Medicine
  • Thoracic Surgery
  • Pulmonology

Background:

  • Tracheal tumors are rare, with chondrohamartomas being benign cartilaginous neoplasms.
  • Misdiagnosis of airway obstruction as asthma can delay appropriate treatment.

Observation:

  • An elderly female non-smoker with a history of asthma presented with intractable cough, shortness of breath, and wheezing.
  • Initial management for severe asthma for two decades failed to alleviate symptoms.

Findings:

  • High-resolution CT scan revealed a large intraluminal tracheal polypoid mass.
  • Flexible bronchoscopy confirmed a pedunculated mass in the distal trachea.
  • Surgical removal via rigid bronchoscopy, laser, electrocautery, and argon ablation was successful.

Implications:

  • This case underscores the necessity of investigating persistent respiratory symptoms unresponsive to asthma treatment.
  • Early diagnosis and surgical intervention for tracheal chondrohamartoma can lead to complete symptom resolution.
  • Highlights the differential diagnosis for severe asthma, especially in non-smokers.