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COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC
Yung On Cheng1, Sajesh K Veettil2, M Sakil Syeed3
1School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
Diode laser and amlexanox are effective for recurrent aphthous ulceration (RAU) pain and diameter reduction. Iralvex best reduces ulcer duration, but more research is needed for laser therapy efficacy.
Area of Science:
- Oral Medicine
- Evidence-Based Dentistry
- Pharmacology
Background:
- Recurrent aphthous ulceration (RAU) is a prevalent oral condition affecting millions globally.
- Effective management strategies for RAU are continuously sought to improve patient outcomes.
- Assessing the comparative efficacy and safety of existing RAU interventions is crucial.
Conclusions:
- Several interventions, including diode laser and amlexanox, show superior efficacy over placebo for RAU management.
- Laser therapy presents a potential option for pain management in RAU, though evidence is limited.
- Further high-quality RCTs with larger sample sizes are recommended to solidify evidence for RAU interventions.
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