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Pancreatic Cancer's PD1-Roadblock: When T-Cell Reinvigoration Is Not Enough

Varintra E Lander1,2, David G DeNardo1,2,3

  • 1Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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