Related Experiment Video
Updated: Jul 9, 2025

08:39
A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
1.7K
ACR Appropriateness Criteria® Dialysis Fistula Malfunction.
, Mikhail C S S Higgins1, Matthew Diamond2
1Boston University School of Medicine, Boston, Massachusetts.
Journal of the American College of Radiology : JACR
|December 1, 2023
Summary
Maintaining dialysis access is crucial for end-stage renal disease patients. This guide systematically evaluates dialysis access dysfunction, offering evidence-based approaches for improved patient outcomes.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Dialysis access is critical for end-stage renal disease (ESRD) patient survival and treatment cost reduction.
- Access quality directly impacts dialysis efficacy and patient longevity.
- All dialysis access methods eventually face dysfunction and failure.
Purpose of the Study:
- To systematically evaluate and appraise variants of dialysis access dysfunction.
- To provide evidence-based guidelines for managing thrombotic, nonthrombotic, and infectious access complications.
- To outline diagnostic and interventional strategies for restoring arteriovenous access function.
Main Methods:
- Systematic analysis of peer-reviewed medical literature.
- Application of Grading of Recommendations Assessment, Development, and Evaluation (GRADE) principles.
- Utilizing the RAND/UCLA Appropriateness Method for imaging and treatment procedure evaluation.
- Incorporating expert opinion where literature is lacking or equivocal.
Main Results:
- Dialysis access dysfunction is categorized into thrombotic, nonthrombotic, and infectious complications.
- Restoration strategies include diagnostic imaging, clinical consultation, percutaneous interventions, and surgical management.
- The American College of Radiology Appropriateness Criteria provide a framework for evidence-based management.
Conclusions:
- A systematic, evidence-based approach is essential for managing dialysis access dysfunction.
- Multidisciplinary collaboration and established methodologies ensure appropriate patient care.
- Optimizing dialysis access management improves ESRD patient morbidity, mortality, and quality of life.
Related Concept Videos
Dialysis
322
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
322
Renal Failure: Dose Adjustments
95
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
95
Factors Affecting Renal Clearance: Renal Impairment
99
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
99

